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Top About What’s new Member Gallery Careers Access Contact JPN/ENG --> Top About What’s new Member Gallery Careers Access Contact JPN/ENG What's new PRIMe news What’s going on at PRIMe? Check out the latest news here. Top What's new ACIDES: on line monitoring of forward genetic screens for protein engineering Category All Awards Events Research Topics Archives 2024 2023 2022 Research Dec 26, 2023 ACIDES: on line monitoring of forward genetic screens for protein engineering Protein screening is an experimental method employed to identify, analyze, and characterize proteins according to their structure and functions. This process plays a crucial role in diverse applications, including drug discovery and disease diagnostics.Takahiro Nemoto (WPI-PRIMe), Deniz Dalkara (Institut de la Vision, Sorbonne Université), Ulisse Ferrari(Institut de la Vision, Sorbonne Université) and the research group developed ACIDES (Accurate Con dence Intervals for Directed Evolution Scores), a computational method to empower the analysis of directed evolution and deep mutational scanning experiments. ACIDES will allow experimentalists to reliably estimate variant performance, aid protein engineering and research pipelines in a range of applications, including gene therapy. TitleACIDES: on line monitoring of forward genetic screens for proteinengineeringAuthorTakahiro Nemoto , Tommaso Ocari , Arthur Planul , Muge Tekinsoy , EmiliaA. Zin , Deniz Dalkara and Ulisse FerrariDOIhttps://doi.org/10.1038/s41467-023-43967-9JournalNature CommunicationsPublished dateDecember 26, 2023 Back to list